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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195017b8ce06539e5364ea833e658cf20751bd817606eb01f51496eb17d7fb6b' 
  AND token = 'iHF3bAMlWABriRj7aGELkPBiY79NZCjn83t20ckuZYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}