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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4944f7fe8cd0681f7c30d521e7c9f15f78b9c8cb25d0ab6817d4d3ed3f4f0279' 
  AND token = 'S9mop1wrPpEin462PK0+vyAMmiZAjXgGbn2CbUFaRmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}