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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '823139887357274c9f06b5e7fd9df3f21af72c1faf1b5e02b0f6653fdf993987' 
  AND token = '+cPkja0DmiuXZSfOc+CcIrc2lVKaZiLCGVrCQfCc+YE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}