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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '409a12eb77ecdc42fdcba1423a5cee53624a14cd06772a452f84aaa763fb97d0' 
  AND token = '9N4i7wkMz/8NW6iAMBSy3+7/HJBzcSgmm/LDzmC/+gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}