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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be320b82431eeaa464fdae5fb5b24d0107d82c83b5732e28c3c1beb7374b6a53' 
  AND token = 'kwxS6xXd7ly3ZeCah6/iunsjLBse5v9Q8mHiJ7dFnJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}