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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40f5b25f1f1d5c0b4d40bf621607a04d9b3b98de3287bc7e676dd08e29f4d285' 
  AND token = 'd1pPliwOqW8Mh7bB0WCWQK5PzVXc9TDBIyF4RUkQee0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}