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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9498cc8857cfaacc2761617a79e5a64536b649767ba7bd1d78eda601f4ff6faa' 
  AND token = 'yoR/ImY0MozAzVqfG83bRUyYvOAjBukBrAik/PBYw3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}