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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b122b3ec9328c3bc1753b6cfbcc03123afe5faeccad037abd71802867970c4f' 
  AND token = 'rghZW/tV6vYXAe0gFXf+Tby2GbVrboM5ukl5iqjJCjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}