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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a45c435b430265dc2740ad0dc3c18dfc526b0495d1827f4299c055c7ed9add7' 
  AND token = '2ARnRdLLioToMPvsmCW7VH8BZ4rvlEkQWV5+3ZVmapI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}