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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b961b911a4761b0790d6dbb5d636d72dd527abf9ce26cfc2f8c5e7f8db0656' 
  AND token = 'X0o6nhxf1wjzdfLJXInISR+dygDxAp+//ttkLiRHKM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}