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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd501bb45bad1c4307cf2e90befe49a8dc7c1d34f6f8a4dfb84322edc92d10a0a' 
  AND token = '+M8Zs+dqqm2t7/mTLy3ywvSJt6XoQ0qTIbxZKRWuUqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}