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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '148ac58fb81f0ea4246834633c38d81f016e04fdc1bb4d550a2b1444f0d0c3d1' 
  AND token = '0vhzM2jRJENLYiO9l5VqXaPoLnzlgVYH1mRYkfWZTJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}