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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd72123df8f629192254cbc888f228e92e1001173d521d1300160e204474f04e4' 
  AND token = '8RBc9YRPS4sri5S1trONW7HXBjFngkDjb4c8m2x2YxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}