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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1124e412bbb89aecc4ca178ed96384cf163b71b5b17b2968a89742147a611202' 
  AND token = 'LwqVOhpRX6eQL+fptDlXnMvOMNniBSBFzo9yTm3x95g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}