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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f66de00ede8c0e2a818f14b9278e721c3edf891702fe9ab9b7f35c546ef2296' 
  AND token = 'l0aOrht9ztHDbzf+it6NCqjXlaQ/oVKFlBjqWhy8eEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}