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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7721f4a1bf53c729f9ec082b3dc563ec6fa63548476b8912264ea0b622983eef' 
  AND token = '3m7vVvlwIXF1m5Qi0Z5EmOo9GkBpvv7Bfoh96Emskb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}