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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ff20b05a72aec187f94d8c53893c427df2224064b540b5b71ec5c912fb5bdb5' 
  AND token = 'Z6QTTeeS6sdSP37vsir6fzjFUwtPB0WKyBEqpUEWNc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}