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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c502162d4fc744841900c0d1b9788b7bd451228b948c45813480a853bbed035c' 
  AND token = '1YGCNvmfdx46PeCLkoUVR9zKyVRo3zpRA5fdLQr+zD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}