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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '228baf2fca38a8d37c8838aa7acedebb49eb9b140b8c29a4013a6e0d25b67d05' 
  AND token = 'LuDzlJoMy13UL/jQOrMgNhYGax3SwX/Uzxp5xSdMSpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}