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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5301ad0fbbc8ff254b40a262d0d4e2f5f4020895d1605a5bfabec8548449d62' 
  AND token = 'njOxRVfSWFXK07KHvFHiOnME4orGm3avcBIAah6ttss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}