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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e3ec5d0521c005564b2f53b30dd8c4f2535d012a64bdb539e144abe975eea7' 
  AND token = 'ZnD4AcFzGyKHxw2eLobCYcJG4FXmwz5G72DbdMN1/pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}