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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfe9de0045bbe70c0c702eb3b3aced9262062560e3d6c465653040bd445d4918' 
  AND token = 'c9qXSjdVtgX+Mn5uLuSYjkPMLFmCbmDOsNDcL31awdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}