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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1410c51d160b07f2921f22fbe9df0226bcf70dd63eb1510720ab0c68b48a5ad' 
  AND token = 'DbtPTgBg9qf+3M2MIdi56nMxc4vHRIRqWybrrxRVwJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}