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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '247301f1ce69c2eae975f2e055e0331ff4906dc92e0f0062ac93d2f70d8247c1' 
  AND token = 'JYPwzd0yZsqpBYEQLyGpMgizddq+d6Q+5UIlL4CrsEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}