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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c31d5a181260144f1f01d12eb0e9360eee66789840e978cc352fbc9ceb46c03f' 
  AND token = 'ZNNLr1F3PFgg3CvoDOVZRuDLgXmyjKAipxz6nuo33RM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}