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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7c8573a5c0154af3d9d486a830951ecb5c0598f70d630951aab04397341556' 
  AND token = 'pWvUkxWqKx8AhUrQsHurqLrm2nWQv3fAqau/3rW5Qac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}