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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bd789abfe1c4e0d077720c021355c46f687809c5a65de63de7389ce42c8ff9e' 
  AND token = 'v6N5VEVgHwSPHuoebTRRlK7iK/oraRvhVJ7MgOuxQsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}