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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e72e29ef09843ac4bde365676cc89e17a484320ef715c0a0a5ce744db490492b' 
  AND token = 'ERl5c3zh259TXc8SbXPaG/5wYlyvN4tjLaPfSYj5TJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}