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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c83d0ac613618377abde6f6af238000e813bac201bebb73c34d8eaeb54c2f0' 
  AND token = '6lyxbtxWo9RypG+t7VHAz25q4ZXNFZfGGw5agBXAMfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}