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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5119d91c6ad54ad0b5043b715c704b9702c6493f6ce3446aceb6b9bb18e5feb' 
  AND token = 'tfREBoHRZsi2zWPcsvt1kxChHEypLka0KaxpqqlZ3Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}