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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c5451536c03866b94f04fe6d50b73821db91d98293b8ba80011965d50a53760' 
  AND token = 'CGicuB6qBM32DOajIhersMqO9XSzTsv+6L5u1vn/GmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}