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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6c605b9b2a3769a3fbe144b5426bba71e2900d418962074886049427fdf442' 
  AND token = 'H3IJSAG7tZQ9LcGJTq739mnrvR4CWu/FEGpo7md5Rxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}