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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75208a93f53bd2585f40ed10bf1b207ac5aaf8b3617758d89b5af41742fda011' 
  AND token = 'AC5/V7hS1uHBIhndfRZMIsLFXm1T6E2Lz8uVEY2bxzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}