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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cedc337c2328dfa52b6b3727634cbc1489efc3b6d1e095d2842c5eafed59043a' 
  AND token = '37bWVwseQAWL05hXHn72v9WtVX//sh7POCSVZjU1FYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}