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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f33a01866710242d2c5a6df67e34539752614b5cd027444c8044b655ce9b324' 
  AND token = 'TqbRY2X52Nfu66t8XSx8Bxhl0lsV5jiXLU10Tpc8nCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}