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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b73c791ddc774fe847ac2ed6ad2cac544c79084870152544dbdf7897b418f283' 
  AND token = 'SW8AFb1xH2kQfpi3EnbUa9HQaU8q+VZNHE3xEr56VSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}