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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ceb112dae9d099e7d07dc56f9bef4ea4a882a5a3e753f3fb67b7987cb0a45901' 
  AND token = 'Bwn4qBw3tYMUbmub/eUC7FSTS4NN5W/8sUpfaxzy24Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}