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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a303722301b1945a133d89f0a477dda3c41fc60a34f32a5d9a97544f745c683' 
  AND token = 'nIvWNtaWanlxYSFK6UjB6+F7ErWQCM/U1mStyU1EVgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}