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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f5d2a51445f55f51932f232d9a7763e2f9e8d2989c74ed590235625955f41c' 
  AND token = 'XLeRFGM/8ARmiapnV9N8I83kxBRsSJV+neTtxmS9RJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}