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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180b595c300fa5572a71ef071925e3fa624f8cc7da2480bcb72c2d4ee235b8b2' 
  AND token = '+o64qsDD1cwbp1jJMO1qGx8X5V0F4QeastCF4XtWkFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}