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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22afa57a98564f13e1383099d3f0f5c6640b6a0b93be2c8899170582ad2651a4' 
  AND token = 'WZ5rr168dwsNU9eHNIz+G2Vxn+o1veTmMeKIbZpzooI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}