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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c28089a8ca7ec16f70ab6f4c66dbb6c755d989396ac5899c3acf778c8661f18' 
  AND token = 'p8hfQxQ9gKFwReBy9b6N5eP6SFolz+O8gjg2Z0k18N0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}