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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73768bdf75b8872e3a7a90d6eaf83f2ebb087fc84f6d6079b3f75b2bed3a1f58' 
  AND token = 'uFV4IB6VhZmuCkncapBurRS29zilIUGL0xDgv7ct9zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}