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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8de0e04c7f39b1c9e8b60949cb6de7b1547e47487f20b61e0f2504c1d6c9fad' 
  AND token = 'Em3FmY1oQHG4Lmi7QCcuu/kYy2vB4ndr9I1tV2FIm2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}