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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '537eb44be8fb6cb38160dff7253fe19f5ba83bd4b48e70803f9910e327106e23' 
  AND token = 'jS3t3PrKbO8+Zakg8LD8jJ3tBZDvx6j4QNdbEyyoBmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}