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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9511334da8dae9d061e476b73c68179e4bd04ce720e8c4d3b72752dd5aa2ba8' 
  AND token = 'zg/S/x3q+GUskfSjE3RKayTnYSgcJuOgn6RTHYmTa0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}