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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc169d49cd2b2380407d17c3b939bd7505e7ed08c55010ae515b5d533a594cab' 
  AND token = '/GNOS0Al8sUuUSFQHmw7zoMBVQdgqM8Btzc/cyQCQcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}