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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a66e12630bcea4d34c1c3d128b5641396f9088f32e2e05370d489ec478c6e50' 
  AND token = 'X/BDsIuNlvIgCaF8KtW+ibZm+NcLjmGuROc0VdmsE4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}