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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c81b61238cfa5d44e4d6fc08b01bd895df4b0b831ca549344d9b5b8f274f63e4' 
  AND token = 'pfx1vMIuaGWyfOBsKlf6qyoqmYNtstVDvBex2n+jXdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}