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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d222503bfc668a852e189237fb1787e7e49a0f591551ee9e68061b531530f17' 
  AND token = 'C0DC5TvmM6rGAuRA17WLjqGbqbsV5R1kfa7Teg6Y/CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}